G159S (p.Gly159Ser) variant of IRAK1 (P51617)
G159S (p.Gly159Ser) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
G159S (p.Gly159Ser) variant details
- p.Gly159Ser
- ExAC rs781996777
- TOPMed rs781996777
- gnomAD rs781996777
- Missense
- Variant Prioritization Score for Impact Estimate 0.111
- REVEL 0.13
- CADD 2.75
- PolyPhen-2 0.01
- SIFT 0.63
- Most common in the South Asian population (allele frequency 0.0002)
- Structural context available