G14S (p.Gly14Ser) variant of IRAK1 (P51617)
G14S (p.Gly14Ser) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
G14S (p.Gly14Ser) variant details
- p.Gly14Ser
- TOPMed rs2065769359
- Missense
- Variant Prioritization Score for Impact Estimate 0.212
- REVEL 0.08
- CADD 23.50
- PolyPhen-2 0.41
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 5.8e-06)
- Structural context available