E9K (p.Glu9Lys) variant of IRAK1 (P51617)
E9K (p.Glu9Lys) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
E9K (p.Glu9Lys) variant details
- p.Glu9Lys
- cosmic curated COSV10514
- TOPMed rs1306839426
- gnomAD rs1306839426
- Missense
- Variant Prioritization Score for Impact Estimate 0.202
- REVEL 0.04
- CADD 17.90
- PolyPhen-2 0.03
- SIFT 0.27
- Most common in the Non-Finnish European population (allele frequency 2e-05)
- Structural context available