A47S (p.Ala47Ser) variant of IRAK1 (P51617)
A47S (p.Ala47Ser) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
A47S (p.Ala47Ser) variant details
- p.Ala47Ser
- TOPMed rs1342744049
- gnomAD rs1342744049
- Missense
- Variant Prioritization Score for Impact Estimate 0.292
- REVEL 0.23
- CADD 17.30
- PolyPhen-2 0.38
- SIFT 0.99
- Most common in the Latino/Admixed American population (allele frequency 8.2e-05)
- Structural context available