A15P (p.Ala15Pro) variant of IRAK1 (P51617)
A15P (p.Ala15Pro) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
A15P (p.Ala15Pro) variant details
- p.Ala15Pro
- ExAC rs782079065
- gnomAD rs782079065
- Missense
- Variant Prioritization Score for Impact Estimate 0.309
- REVEL 0.17
- CADD 24.50
- PolyPhen-2 0.55
- SIFT 0.01
- Most common in the East Asian population (allele frequency 5.6e-05)
- Structural context available