A146V (p.Ala146Val) variant of IRAK1 (P51617)
A146V (p.Ala146Val) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
A146V (p.Ala146Val) variant details
- p.Ala146Val
- ExAC rs782013472
- gnomAD rs782013472
- Missense
- Variant Prioritization Score for Impact Estimate 0.22
- REVEL 0.15
- CADD 20.80
- PolyPhen-2 0.53
- SIFT 0.37
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available