A12V (p.Ala12Val) variant of IRAK1 (P51617)
A12V (p.Ala12Val) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
A12V (p.Ala12Val) variant details
- p.Ala12Val
- ExAC rs781859481
- TOPMed rs781859481
- gnomAD rs781859481
- Missense
- Variant Prioritization Score for Impact Estimate 0.121
- REVEL 0.08
- CADD 15.40
- PolyPhen-2 0.00
- SIFT 0.19
- Most common in the REMAINING population (allele frequency 3.2e-05)
- Structural context available