A127P (p.Ala127Pro) variant of IRAK1 (P51617)
A127P (p.Ala127Pro) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
A127P (p.Ala127Pro) variant details
- p.Ala127Pro
- TOPMed rs2065763765
- gnomAD rs2065763765
- Missense
- Variant Prioritization Score for Impact Estimate 0.275
- REVEL 0.16
- CADD 4.54
- Most common in the African/African-American population (allele frequency 3.3e-05)
- Structural context available