A115V (p.Ala115Val) variant of IRAK1 (P51617)
A115V (p.Ala115Val) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
A115V (p.Ala115Val) variant details
- p.Ala115Val
- TOPMed rs1190833980
- Missense
- Variant Prioritization Score for Impact Estimate 0.0807
- REVEL 0.04
- CADD 10.30
- PolyPhen-2 0.01
- SIFT 0.26
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available