A106S (p.Ala106Ser) variant of IRAK1 (P51617)
A106S (p.Ala106Ser) in IRAK1 (P51617) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
A106S (p.Ala106Ser) variant details
- p.Ala106Ser
- TOPMed rs2065764533
- gnomAD rs2065764533
- Missense
- Variant Prioritization Score for Impact Estimate 0.074
- REVEL 0.04
- CADD 6.07
- PolyPhen-2 0.06
- SIFT 0.56
- Most common in the Non-Finnish European population (allele frequency 1.9e-05)
- Structural context available