P190S (p.Pro190Ser) variant of IRAG1 (Q9Y6F6)
P190S (p.Pro190Ser) in IRAG1 (Q9Y6F6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
P190S (p.Pro190Ser) variant details
- p.Pro190Ser
- cosmic curated COSV70212
- Missense
- Variant Prioritization Score for Impact Estimate 0.257
- REVEL 0.06
- MetaLR 0.06
- MetaSVM -1.11
- CADD 22.50
- PolyPhen-2 0.25
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available