G316D (p.Gly316Asp) variant of IRAG1 (Q9Y6F6)
G316D (p.Gly316Asp) in IRAG1 (Q9Y6F6) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
G316D (p.Gly316Asp) variant details
- p.Gly316Asp
- rs758893178
- NCI-TCGA Cosmic COSV7021
- cosmic curated COSV70213
- ExAC rs758893178
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.226
- AlphaMissense 0.19
- MetaLR 0.04
- MetaSVM -1.06
- SIFT 0.04
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available