Y171F (p.Tyr171Phe) variant of INSR (Insulin receptor)
Y171F (p.Tyr171Phe) in INSR (Insulin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
Y171F (p.Tyr171Phe) variant details
- p.Tyr171Phe
- gnomAD rs1967772190
- Missense
- Variant Prioritization Score for Impact Estimate 0.481
- REVEL 0.43
- MetaLR 0.43
- MetaSVM -0.37
- CADD 22.20
- SIFT 0.03
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available