T3I (p.Thr3Ile) variant of INSR (Insulin receptor)
T3I (p.Thr3Ile) in INSR (Insulin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
T3I (p.Thr3Ile) variant details
- p.Thr3Ile
- Ensembl rs1968567916
- Missense
- Variant Prioritization Score for Impact Estimate 0.231
- REVEL 0.08
- MetaLR 0.17
- MetaSVM -0.94
- CADD 15.30
- PolyPhen-2 0.00
- SIFT 0.03
- Most common in the East Asian population (allele frequency 4.3e-05)
- Structural context available