T107A (p.Thr107Ala) variant of INSR (Insulin receptor)
T107A (p.Thr107Ala) in INSR (Insulin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
T107A (p.Thr107Ala) variant details
- p.Thr107Ala
- gnomAD rs1248231684
- Missense
- Variant Prioritization Score for Impact Estimate 0.376
- REVEL 0.26
- MetaLR 0.33
- MetaSVM -0.61
- CADD 18.40
- PolyPhen-2 0.04
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available