S77G (p.Ser77Gly) variant of INSR (Insulin receptor)
S77G (p.Ser77Gly) in INSR (Insulin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
S77G (p.Ser77Gly) variant details
- p.Ser77Gly
- ExAC rs747157246
- gnomAD rs747157246
- Missense
- Variant Prioritization Score for Impact Estimate 0.658
- REVEL 0.73
- MetaLR 0.67
- MetaSVM 0.51
- CADD 25.50
- PolyPhen-2 0.93
- SIFT 0.00
- Most common in the East Asian population (allele frequency 5e-05)
- Structural context available