S166C (p.Ser166Cys) variant of INSR (Insulin receptor)
S166C (p.Ser166Cys) in INSR (Insulin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
S166C (p.Ser166Cys) variant details
- p.Ser166Cys
- TOPMed rs267605760
- gnomAD rs267605760
- Missense
- Variant Prioritization Score for Impact Estimate 0.683
- REVEL 0.62
- MetaLR 0.68
- MetaSVM 0.51
- CADD 26.10
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available