R110W (p.Arg110Trp) variant of INSR (Insulin receptor)
R110W (p.Arg110Trp) in INSR (Insulin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.79 / 1. The record also includes population frequency data and structural context.
R110W (p.Arg110Trp) variant details
- p.Arg110Trp
- cosmic curated COSV57167
- ExAC rs762765697
- gnomAD rs762765697
- Missense
- Variant Prioritization Score for Impact Estimate 0.785
- REVEL 0.93
- MetaLR 0.78
- MetaSVM 0.78
- CADD 26.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available