M83T (p.Met83Thr) variant of INSR (Insulin receptor)
M83T (p.Met83Thr) in INSR (Insulin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
M83T (p.Met83Thr) variant details
- p.Met83Thr
- TOPMed rs1967783364
- gnomAD rs1967783364
- Missense
- Variant Prioritization Score for Impact Estimate 0.453
- REVEL 0.39
- MetaLR 0.41
- MetaSVM -0.43
- CADD 21.40
- PolyPhen-2 0.02
- SIFT 0.04
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available