L96F (p.Leu96Phe) variant of INSR (Insulin receptor)
L96F (p.Leu96Phe) in INSR (Insulin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
L96F (p.Leu96Phe) variant details
- p.Leu96Phe
- ExAC rs752292214
- gnomAD rs752292214
- Missense
- Variant Prioritization Score for Impact Estimate 0.622
- REVEL 0.74
- MetaLR 0.78
- MetaSVM 0.53
- CADD 24.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available