L88F (p.Leu88Phe) variant of INSR (Insulin receptor)
L88F (p.Leu88Phe) in INSR (Insulin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data and structural context.
L88F (p.Leu88Phe) variant details
- p.Leu88Phe
- Ensembl rs1967782992
- Missense
- Variant Prioritization Score for Impact Estimate 0.731
- REVEL 0.78
- MetaLR 0.76
- MetaSVM 0.53
- CADD 23.10
- SIFT 0.00
- Population evidence available
- Structural context available