I62T (p.Ile62Thr) variant of INSR (Insulin receptor)
I62T (p.Ile62Thr) in INSR (Insulin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.83 / 1. The record also includes population frequency data and structural context.
I62T (p.Ile62Thr) variant details
- p.Ile62Thr
- gnomAD rs1388989393
- Missense
- Variant Prioritization Score for Impact Estimate 0.829
- REVEL 0.94
- MetaLR 0.88
- MetaSVM 1.00
- CADD 26.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available