I146F (p.Ile146Phe) variant of INSR (Insulin receptor)
I146F (p.Ile146Phe) in INSR (Insulin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
I146F (p.Ile146Phe) variant details
- p.Ile146Phe
- TOPMed rs1967775054
- gnomAD rs1967775054
- Missense
- Variant Prioritization Score for Impact Estimate 0.656
- REVEL 0.77
- MetaLR 0.65
- MetaSVM 0.29
- CADD 23.60
- PolyPhen-2 0.65
- SIFT 0.00
- Population evidence available
- Structural context available