G5R (p.Gly5Arg) variant of INSR (Insulin receptor)
G5R (p.Gly5Arg) in INSR (Insulin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
G5R (p.Gly5Arg) variant details
- p.Gly5Arg
- 1000Genomes rs1410352680
- gnomAD rs1410352680
- Missense
- Variant Prioritization Score for Impact Estimate 0.166
- REVEL 0.06
- MetaLR 0.14
- MetaSVM -1.01
- CADD 15.30
- PolyPhen-2 0.00
- SIFT 0.93
- Most common in the 1KG:GBR population (allele frequency 0.0057)
- Structural context available