G4W (p.Gly4Trp) variant of INSR (Insulin receptor)
G4W (p.Gly4Trp) in INSR (Insulin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
G4W (p.Gly4Trp) variant details
- p.Gly4Trp
- gnomAD rs1370875449
- Missense
- Variant Prioritization Score for Impact Estimate 0.3
- REVEL 0.29
- MetaLR 0.21
- MetaSVM -0.85
- CADD 21.60
- PolyPhen-2 0.15
- SIFT 0.00
- Population evidence available
- Structural context available