G37S (p.Gly37Ser) variant of INSR (Insulin receptor)
G37S (p.Gly37Ser) in INSR (Insulin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
G37S (p.Gly37Ser) variant details
- p.Gly37Ser
- cosmic curated COSV57159
- ExAC rs748177213
- TOPMed rs748177213
- gnomAD rs748177213
- Missense
- Variant Prioritization Score for Impact Estimate 0.233
- REVEL 0.16
- MetaLR 0.22
- MetaSVM -0.85
- CADD 14.50
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the African/African-American population (allele frequency 7.3e-05)
- Structural context available