G32R (p.Gly32Arg) variant of INSR (Insulin receptor)
G32R (p.Gly32Arg) in INSR (Insulin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
G32R (p.Gly32Arg) variant details
- p.Gly32Arg
- TOPMed rs1310944135
- gnomAD rs1310944135
- Missense
- Variant Prioritization Score for Impact Estimate 0.303
- REVEL 0.12
- MetaLR 0.26
- MetaSVM -0.81
- CADD 21.50
- PolyPhen-2 0.01
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 0.0002)
- Structural context available