G27S (p.Gly27Ser) variant of INSR (Insulin receptor)
G27S (p.Gly27Ser) in INSR (Insulin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
G27S (p.Gly27Ser) variant details
- p.Gly27Ser
- TOPMed rs1968563279
- Missense
- Variant Prioritization Score for Impact Estimate 0.303
- REVEL 0.08
- MetaLR 0.19
- MetaSVM -0.97
- CADD 18.40
- PolyPhen-2 0.00
- SIFT 0.42
- Population evidence available
- Structural context available