D39Y (p.Asp39Tyr) variant of INSR (Insulin receptor)
D39Y (p.Asp39Tyr) in INSR (Insulin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.83 / 1. The record also includes population frequency data and structural context.
D39Y (p.Asp39Tyr) variant details
- p.Asp39Tyr
- gnomAD rs1408976613
- Missense
- Variant Prioritization Score for Impact Estimate 0.834
- REVEL 0.92
- MetaLR 0.69
- MetaSVM 0.49
- CADD 26.00
- SIFT 0.00
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available