A9P (p.Ala9Pro) variant of INSR (Insulin receptor)
A9P (p.Ala9Pro) in INSR (Insulin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
A9P (p.Ala9Pro) variant details
- p.Ala9Pro
- TOPMed rs1417610197
- gnomAD rs1417610197
- Missense
- Variant Prioritization Score for Impact Estimate 0.249
- REVEL 0.25
- MetaLR 0.21
- MetaSVM -0.98
- CADD 10.00
- PolyPhen-2 0.01
- SIFT 0.40
- Most common in the South Asian population (allele frequency 4.1e-05)
- Structural context available