A2S (p.Ala2Ser) variant of INSR (Insulin receptor)
A2S (p.Ala2Ser) in INSR (Insulin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
A2S (p.Ala2Ser) variant details
- p.Ala2Ser
- gnomAD rs1231519485
- Missense
- Variant Prioritization Score for Impact Estimate 0.206
- REVEL 0.12
- MetaLR 0.18
- MetaSVM -0.92
- CADD 16.60
- PolyPhen-2 0.00
- SIFT 0.38
- Population evidence available
- Structural context available