V66M (p.Val66Met) variant of INS (Insulin)
V66M (p.Val66Met) in INS (Insulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
V66M (p.Val66Met) variant details
- p.Val66Met
- cosmic curated COSV10507
- Missense
- Variant Prioritization Score for Impact Estimate 0.304
- REVEL 0.32
- MetaLR 0.61
- MetaSVM -0.28
- CADD 16.70
- PolyPhen-2 0.64
- SIFT 0.21
- Population evidence available
- Structural context available