V63E (p.Val63Glu) variant of INS (Insulin)
V63E (p.Val63Glu) in INS (Insulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
V63E (p.Val63Glu) variant details
- p.Val63Glu
- gnomAD 11-2159997-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.312
- REVEL 0.44
- MetaLR 0.53
- MetaSVM -0.54
- CADD 0.24
- PolyPhen-2 0.01
- SIFT 0.66
- Population evidence available
- Structural context available
- Literature evidence available