T51A (p.Thr51Ala) variant of INS (Insulin)
T51A (p.Thr51Ala) in INS (Insulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
T51A (p.Thr51Ala) variant details
- p.Thr51Ala
- gnomAD rs1410071121
- Missense
- Variant Prioritization Score for Impact Estimate 0.288
- REVEL 0.27
- MetaLR 0.57
- MetaSVM -0.31
- CADD 14.10
- PolyPhen-2 0.03
- SIFT 0.28
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available