Q62K (p.Gln62Lys) variant of INS (Insulin)
Q62K (p.Gln62Lys) in INS (Insulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, published literature, and structural context.
Q62K (p.Gln62Lys) variant details
- p.Gln62Lys
- gnomAD 11-2160788-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.582
- REVEL 0.49
- MetaLR 0.72
- MetaSVM 0.01
- CADD 23.40
- PolyPhen-2 0.66
- SIFT 0.93
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available