P21P (p.Pro21Pro) variant of INS (Insulin)
P21P (p.Pro21Pro) in INS (Insulin) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
P21P (p.Pro21Pro) variant details
- p.Pro21Pro
- rs11564720
- gnomAD 11-2160909-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0814
- CADD 0.11
- Most common in the HGDP:BANTUSOUTHAFRICA population (allele frequency 0.062)
- Structural context available
- Cited in: Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American… (PMID 25741868)