P19S (p.Pro19Ser) variant of INS (Insulin)
P19S (p.Pro19Ser) in INS (Insulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
P19S (p.Pro19Ser) variant details
- p.Pro19Ser
- gnomAD 11-2160917-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.36
- REVEL 0.33
- MetaLR 0.44
- MetaSVM -0.59
- CADD 18.70
- PolyPhen-2 0.01
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available