L7F (p.Leu7Phe) variant of INS (Insulin)
L7F (p.Leu7Phe) in INS (Insulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
L7F (p.Leu7Phe) variant details
- p.Leu7Phe
- gnomAD 11-2160953-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.33
- REVEL 0.33
- MetaLR 0.79
- MetaSVM 0.07
- CADD 9.67
- PolyPhen-2 0.01
- SIFT 0.75
- Population evidence available
- Structural context available
- Literature evidence available