L61M (p.Leu61Met) variant of INS (Insulin)
L61M (p.Leu61Met) in INS (Insulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
L61M (p.Leu61Met) variant details
- p.Leu61Met
- gnomAD 11-2160791-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.473
- REVEL 0.39
- MetaLR 0.68
- MetaSVM -0.25
- CADD 18.40
- PolyPhen-2 0.88
- SIFT 0.22
- Population evidence available
- Structural context available
- Literature evidence available