L3V (p.Leu3Val) variant of INS (Insulin)
L3V (p.Leu3Val) in INS (Insulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and published literature.
L3V (p.Leu3Val) variant details
- p.Leu3Val
- gnomAD 11-2160965-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.571
- REVEL 0.66
- MetaLR 0.90
- MetaSVM 0.81
- CADD 13.20
- PolyPhen-2 0.21
- SIFT 0.12
- Population evidence available
- Literature evidence available