G64W (p.Gly64Trp) variant of INS (Insulin)
G64W (p.Gly64Trp) in INS (Insulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
G64W (p.Gly64Trp) variant details
- p.Gly64Trp
- cosmic curated COSV51747
- Missense
- Variant Prioritization Score for Impact Estimate 0.458
- REVEL 0.46
- MetaLR 0.76
- MetaSVM 0.45
- CADD 19.90
- PolyPhen-2 0.91
- SIFT 0.03
- Population evidence available
- Structural context available