F49F (p.Phe49Phe) variant of INS (Insulin)
F49F (p.Phe49Phe) in INS (Insulin) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
F49F (p.Phe49Phe) variant details
- p.Phe49Phe
- rs148685531
- gnomAD 11-2160825-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.472
- CADD 11.30
- Most common in the African/African-American population (allele frequency 0.00051)
- Structural context available
- Literature evidence available