F25S (p.Phe25Ser) variant of INS (Insulin)
F25S (p.Phe25Ser) in INS (Insulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data, published literature, and structural context.
F25S (p.Phe25Ser) variant details
- p.Phe25Ser
- gnomAD 11-2160898-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.619
- REVEL 0.67
- MetaLR 0.91
- MetaSVM 0.58
- CADD 23.30
- PolyPhen-2 0.96
- SIFT 0.43
- Population evidence available
- Structural context available
- Literature evidence available