D60N (p.Asp60Asn) variant of INS (Insulin)
D60N (p.Asp60Asn) in INS (Insulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
D60N (p.Asp60Asn) variant details
- p.Asp60Asn
- TOPMed rs954838167
- gnomAD rs954838167
- Missense
- Variant Prioritization Score for Impact Estimate 0.384
- REVEL 0.37
- MetaLR 0.66
- MetaSVM -0.14
- CADD 17.40
- PolyPhen-2 0.08
- SIFT 0.40
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available