C43* (p.Cys43Ter) variant of INS (Insulin)
C43* (p.Cys43Ter) in INS (Insulin) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
C43* (p.Cys43Ter) variant details
- p.Cys43Ter
- gnomAD 11-2160843-G-T
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.314
- CADD 33.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available