A58G (p.Ala58Gly) variant of INS (Insulin)
A58G (p.Ala58Gly) in INS (Insulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
A58G (p.Ala58Gly) variant details
- p.Ala58Gly
- ExAC rs770737691
- gnomAD rs770737691
- Missense
- Variant Prioritization Score for Impact Estimate 0.291
- REVEL 0.34
- MetaLR 0.47
- MetaSVM -0.39
- CADD 15.00
- SIFT 0.04
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available