V18I (p.Val18Ile) variant of IL7R (P16871)
V18I (p.Val18Ile) in IL7R (P16871) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
V18I (p.Val18Ile) variant details
- p.Val18Ile
- cosmic curated COSV10514
- TOPMed rs1320815333
- gnomAD rs1320815333
- Missense
- Variant Prioritization Score for Impact Estimate 0.395
- REVEL 0.21
- CADD 22.90
- PolyPhen-2 0.57
- SIFT 0.07
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available