V11F (p.Val11Phe) variant of IL7R (P16871)
V11F (p.Val11Phe) in IL7R (P16871) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
V11F (p.Val11Phe) variant details
- p.Val11Phe
- cosmic curated COSV10731
- TOPMed rs1759660556
- gnomAD rs1759660556
- Missense
- Variant Prioritization Score for Impact Estimate 0.263
- REVEL 0.33
- CADD 1.36
- PolyPhen-2 0.03
- SIFT 0.56
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available