T6K (p.Thr6Lys) variant of IL7R (P16871)
T6K (p.Thr6Lys) in IL7R (P16871) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
T6K (p.Thr6Lys) variant details
- p.Thr6Lys
- ExAC rs771047572
- TOPMed rs771047572
- gnomAD rs771047572
- Missense
- Variant Prioritization Score for Impact Estimate 0.366
- REVEL 0.36
- CADD 10.90
- PolyPhen-2 0.07
- SIFT 0.11
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available