T6I (p.Thr6Ile) variant of IL7R (P16871)
T6I (p.Thr6Ile) in IL7R (P16871) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
T6I (p.Thr6Ile) variant details
- p.Thr6Ile
- ExAC rs771047572
- TOPMed rs771047572
- gnomAD rs771047572
- Missense
- Variant Prioritization Score for Impact Estimate 0.248
- REVEL 0.16
- CADD 10.20
- PolyPhen-2 0.04
- SIFT 0.15
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available